cell shaded is about the closest that is possible, the engine can't tell which edges are supposed to be thickened as in anime it's not normaly just the outline. Also most skins are pre renderd onto the model so if you could get it to work somehow without the textures baked onto the model then you'd need a pretty good pc to run a game that has a fairly low poly count, cell shading is kind of the closest that you can get.
Also in anime perspective is often off but it just gives the impresion of deph etc. i can't think of a way you could make an engine emulate that...
Don't you think if it was possible it would have been done?
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