I usually come from college/work, get to my room, remove my shoes and socks and let out one big "aahhhh..." of relief. Then I go barefoot for the entire day (only while I'm home, of course). If it's winter and the floor is cold (no carpet here), I will wear some thin slippers. So yeah, I don't think anything beats the comfort of not wearing shoes. But hey, I know some people that can't stand being without some clothing on their foot and will usually wear flip flops, crocs, etc.

What about you?