you may want to keep an eye on this indie game: Faster Than Light.
i guess you probably have read about it already.
im a bit hopeful for it although it is still single player at the moment.
it seems to have a lot of player enthusiasm because of its strong detail to ship management
http://www.ftlgame.com/

there are other shipbuilder sims out there. this one is still in development :-
http://www.starshipcorporation.com/