Sounds like you are looking for an Isometric Mobile MMO.
There aren't too many mobile games that have the life skills that runescape has, but there are a few game with multiplayer elements are are grind/loot based.
The closest game would be RPG MO. It's ok.
IMO the World of Magic has been around for ages.
The Greedy Cave 2 allows you to party with people to fight mobs and get loot.
Grow Stone
Mirage Realms
Upcoming:
Ragnarok M: Eternal Love looks like it might be closer to the original RO more than the other Mobile games.
